CLINICAL UPDATES
from SpectraCell Laboratories, Inc.
October 2009 - Vol. 2009, Issue 010
In This Issue…
- Carnitine therapy reduces hypertension
- Vitamin D deficiency increases risk of anemia
- Glutathione depletion common in celiac patients
- Homocysteine hurts telomeres while HDL helps them
- Low antioxidant status increases risk of pre-eclampsia
CLINICAL UPDATE - Carnitine therapy reduces hypertension
32 non-diabetic patients with increased cardiovascular risk were given oral acetyl-L-carnitine twice daily for 24 weeks. The carnitine therapy safely reduced hypertension, insulin resistance and glucose tolerance.
(Hypertension, September 2009)
LINK to ABSTRACT Ameliorating hypertension and insulin resistance in subjects at increased cardiovascular risk: effects of acetyl-L-carnitine therapy.
CLINICAL UPDATE - Vitamin D deficiency increases risk of anemia
Vitamin D and hemoglobin levels were measured on 554 people. An association was found between vitamin D deficiency and risk of anemia, supporting the hypothesis that vitamin D plays a role in the production of red blood cells.
(Annals of Hematology, October 2009)
LINK to ABSTRACT Vitamin D deficiency and anemia: a cross-sectional study.
CLINICAL UPDATE - Glutathione depletion common in celiac patients
Intestinal biopsies of 39 pediatric celiac patients were compared to 19 control patients and researchers found that glutathione-based antioxidant capacity was significantly reduced in the celiac patients.
(Clinical Biochemistry, September 2009)
LINK to ABSTRACT Antioxidant status and lipid peroxidation in small intestinal mucosa of children with celiac disease.
CLINICAL UPDATE - Homocysteine hurts telomeres while HDL helps them
A study on the telomeres of 90 adults demonstrated a significant inverse correlation between telomere length and homocysteine in men. Similarly, in a study on over 650 adults, slower telomere shortening was observed in those with high levels of HDL cholesterol.
(Rejuvenation Research, September 2009)
(Atherosclerosis, August 2009)
LINK to ABSTRACT Telomere Length in Lymphocytes of Older South Australian Men May Be Inversely Associated with Plasma Homocysteine.
LINK to ABSTRACT Leukocyte telomere length is associated with HDL cholesterol levels: The Bogalusa heart study.
CLINICAL UPDATE - Low antioxidant status increases risk of pre-eclampsia
A review of studies from 1986-2007 concluded that patients with documented cases of pre-eclampsia typically have lower levels of vitamins E and C as well as higher lipid peroxidation markers.
(Obstetrical & Gynecological Survey, September 2009)
LINK to ABSTRACT Lipid peroxidation and antioxidant status in preeclampsia: a systematic review.
